REVISTAS INDEXADAS
Permanent URI for this collectionhttps://hdl.handle.net/20.500.14523/235
Colección de artículos en revistas indexadas (Scopus, WoS, SciELO u otras), con control de versiones y enlaces a indexadores.
News
- Actualización periódica de nuevos registros en REVISTAS INDEXADAS.
Browse
Recent Submissions
Item Dimensional Stability and Technological Performance of 13-Year-Old Simarouba amara Aubl. Thinning Wood: Pathways to High-Value Product Development(MDPI AG, 2026-08-04) Amaringo-Córdova, Luiz Paulo; Ucañay-Ayllon, Tatiana Mildred; Rodríguez-Sotelo, Jefferson Alexander; Fasabi-Pashanasi, Hilter; Mori-Montero, Cesar; Ruiz-Torres, Oscar Amado; Guerra-Arévalo, Wilson Francisco; Guerra-Arévalo, Héctor; Aldava-Pardave, Uriel; Bernaola-Paucar, Rosario Marilú; Vásquez-Vela, Ana Lucía Milagros; López-Galán, Edinson Eduardo; Hemeryth-Bartra, Jhinmy Karc; Rodríguez-Vásquez, Kevin IsaacThe valorization of wood derived from thinning operations in tropical plantations represents an alternative to enhance the sustainability and profitability of forest production systems. This study evaluated the hygroscopic, physical, and machining properties of 13-year-old Simarouba amara Aubl. thinning wood obtained from a plantation established in the Peruvian Amazon. Two planting spacings (2 × 2 m and 3 × 3 m) and three longitudinal stem positions (base, middle, and apex) were analyzed using a factorial design and generalized linear mixed models. Planting density and longitudinal position significantly influenced (p < 0.05) most of the evaluated properties. The saturated moisture content increased from 96.17% at the base to 135.42% at the apex, whereas basic density decreased from 0.45 to 0.30 g cm−3. Volumetric shrinkage ranged from 10.19% to 14.81%, and the dimensional stability index varied between 1.66 and 1.91. The first principal component (PC1) explained 98.4% of the total variance and clearly differentiated the treatments. The wood exhibited excellent performance in planing and molding, good performance in drilling, and fair performance in turning, indicating strong potential for the manufacture of higher value-added products and for sustainable utilization in tropical plantation forests.Item The importance of taxonomic classification of ‘Pashaco’ and ‘Huayruro’ in the Fabaceae family for timber production in Loreto, Peru(Universidade Federal do Paraná, 2024-08-27) Villacorta-Gonzáles, Carlos; Del-Aguila-Mendoza, Lizbeth Carolina; Rios-Paredes, Marcos Antonio; Bartolo-Cuba, John Albert; Silva-Moreno, Henri Frank; Welling, JohannesIn Peru, forest inventories traditionally group different timber species under the same commercial name. The names "pashaco" and "huayruro" in the Amazon exemplify this practice, representing the grouping and commercialization of various Fabaceae species, a family of significant forest and commercial importance in Loreto. This study aimed to taxonomically identify the "pashaco" and "huayruro" individuals a timber company recorded in its forest census and to differentiate each group's species through dendrological characterization. The company's census identified 429 "pashaco" individuals as Albizia niopioides and 150 "huayruro" individuals as Ormosia amazonica. Botanical identification of samples from 80 individuals in each group revealed that the individuals classified as A. niopioides comprised nine species: Schizolobium parahyba var. amazonicum, Dimorphandra cuprea, Pseudopiptadenia suaveolens, Hydrochorea pedicellaris, Enterolobium schomburgkii, Parkia nitida, Parkia igneiflora, Parkia decussata, and Parkia multijuga, with the last being the most common. Similarly, the "huayruro" or Ormosia amazonica classification included Andira macrothyrsa, Batesia floribunda, Ormosia coccinea, Ormosia amazonica, Vataireopsis surinamensis, Vatairea erythrocarpa, Hymenolobium excelsum, Hymenolobium nitidum, and Hymenolobium velutinum, with the latter being the most abundant. This study underscores the need for improved species identification in forest inventories. Dendrological characteristics of stems and leaves can aid in differentiating and identifying these species in forest censuses, fostering sustainable management practices by reducing species grouping and minimizing economic impacts in the timber forest production chain.Item Fermentation Arrest Density Modulates Congener Composition and Sensory Profile in Aromatic Grape Distillates(MDPI AG, 2026-08-12) Gavilan-Figari, Isabel Milagros; García-Hernandez, Karla Patricia; Neyra-Lazaro, Enzo Anthony; Effio-Espinoza, Sebastian Antonio; Bollet, HermanStopping fermentation is a critical, yet insufficiently standardised, step in the production of aromatic grape distillates, as it influences residual sugar, yeast metabolism and the availability of volatile precursors. This study evaluated the must density at the time of fermentation arrest as a process control parameter for Torontel grape distillates. Five treatments were established by halting fermentation at densities ranging from 1.050 to 1.010 g/mL, followed by batch distillation. The distillates were evaluated using physicochemical analyses, including alcohol strength and the concentration of key volatile congeners such as methanol, acetaldehyde and higher alcohols. Furthermore, these analyses were complemented by gas chromatography with flame ionisation detection (GC-FID) and sensory evaluation by experts. Increased must density was associated with higher concentrations of methanol, acetaldehyde and higher alcohols, whereas ethanol content decreased. Although clear differences in chemical composition were observed among the evaluated process conditions, overall sensory acceptability exhibited only limited variation across the fermentation arrest densities. However, distillates obtained from intermediate density levels showed better aromatic balance and sensory harmony. Multivariate analysis suggested that fermentation arrest density was associated with the main patterns of chemical variability observed among the evaluated distillates, whereas its association with overall sensory perception appeared to be more limited. These findings provide a useful framework for optimising fermentation arrest strategies in the production of aromatic partially fermented grape distillates.Item Research Trends in Supercritical Fluid Extraction of Bioactive Compounds: A 30-Year Bibliometric Study from 1995 to 2025(MDPI AG, 2026-07-18) Varas-Condori, Miguel Ángel; Puente-Díaz, Luis; Costa-de-Camargo, Adriano; Barriga-Sánchez, Maritza ElizabethThe extraction of bioactive compounds using supercritical fluids has attracted increasing scientific attention as a sustainable alternative to conventional extraction methods. This study presents a bibliometric analysis aimed at providing an overview of the scientific development, collaboration patterns, and thematic trends in this research field. Bibliographic data were retrieved from the Web of Science Core Collection database for the period 1995–2025, resulting in a dataset of 2159 publications. The records were analyzed using the Bibliometrix package in R and complementary Web of Science tools to evaluate scientific productivity, leading contributors, collaboration patterns, keyword analysis (frequency and co-occurrence), thematic evolution, citation topics, and alignment with the United Nations Sustainable Development Goals. The results reveal sustained growth in scientific production, particularly during the last decade, reflecting the increasing interest in environmentally friendly extraction technologies and the growing demand for natural bioactive compounds. Brazil emerged as the leading contributor, followed by China and Spain. Collaboration patterns indicate the presence of international research partnerships among the most productive countries. Keyword analysis highlights antioxidant activity and polyphenols as the most frequent research topics. Thematic analysis reveals a progressive shift from compound characterization to process optimization and application-oriented research, with increasing emphasis on extraction performance, assisted extraction technologies, and the valorization of agro-industrial by-products as alternative sources of bioactive compounds. These findings provide a comprehensive overview of the evolution and main research directions in this field.Item Municipal sewage sludge management in a changing world: Trends and safe resource recovery(South Sustainability, 2026-06-12) Gavilan-Figari, Isabel Milagros; Naka, AngelicaIn this review, we examine municipal sewage sludge management and resource recovery in relation to United Nations Sustainable Development Goal 6 (SDG 6: Clean Water and Sanitation), circular economy goals and public health protection. Major management alternatives, including agricultural land application, energy recovery, use in construction materials, land reclamation and biofuel production are assessed, along with their technical, regulatory, environmental and social constraints. Based on studies and case examples from diverse global regions, in this review we facilitate comparison of sludge management options and identify context-appropriate strategies amid rapid changes in current regulatory requirements and climatic conditions. The reviewed literature indicates that there is no single optimal pathway for sludge management; rather, the most suitable options are dependent upon sludge characteristics, treatment infrastructure, costs, monitoring capacity, local environmental conditions and relevant legal requirements. Resource recovery pathways can reduce environmental burdens and generate value by recovering energy, nutrients or useful materials, but in many cases they require pre-treatment, reliable process control and adequate monitoring. Although land application can improve soil fertility and organic matter content, it requires careful control of pathogens, heavy metals and other contaminants, in order to protect ecosystems and human health. In this study, we conclude that decision-making processes should take into account life-cycle assessments of sludge management alternatives, comprehensive comparisons of technical, environmental, economic and social aspects, environmental justice considerations, sustainability, governance, and integrated water resources management (IWRM). Such an integrated approach can support safer and more locally appropriate resource recovery pathways, while taking into account factors associated with regional conditions and regulatory frameworks.Item Application of emerging non-thermal pre-germination technologies to optimise the germination of Andean pseudocereals and their use in gluten-free baked products(Springer Science and Business Media LLC, 2026-05-22) Díaz-Llocclla, Marianela; Barriga-Sánchez, Maritza Elizabeth; Calandri, Edgardo; Silvera-Otañe, Gian; Asto-Rodriguez, Emerson MaximoThis review examines three Andean pseudocereals: quinoa (Chenopodium quinoa Willd.), kañiwa (Chenopodium pallidicaule Aellen), and kiwicha (Amaranthus caudatus L.). The focus is on the changes achieved through germination, enhanced by the use of emerging technologies applied as a pre-treatment. These grains are characterized by high-quality proteins with a complete essential amino acid profile, significant dietary fiber content, and diverse bioactive compounds with antioxidant, antihypertensive, and antidiabetic properties. This review covers conventional germination methods and parameters and explores emerging non-thermal technologies used as a pre-germination step. Although substantial research has investigated these technologies in quinoa, studies on kañiwa and kiwicha remain limited. Current evidence indicates that technologies such as ultrasound, high hydrostatic pressure, cold plasma, and magnetic fields can optimize enzymatic activity, reduce antinutrient content, and promote the synthesis of functional compounds. Gluten-free baked products made from germinated flour demonstrate improvements in rheological, textural, and sensory properties. However, challenges persist in defining industrial-scale parameters and addressing the high manufacturing costs of gluten-free products. A bibliometric analysis shows an increasing global interest in gluten-free products, creating commercial opportunities for these Andean pseudocereals. Kañiwa is identified as particularly promising due to its climatic resilience and nutritional value. The conclusion emphasizes the need for further research to optimize processing protocols and validate scaling approaches, thereby enhancing the contribution of pseudocereals to global food security and sustainable development.Item Phylogenomic and comparative genomic analyses of Aeromonas spp. from South American aquatic systems reveal extensive genomic diversity, antimicrobial resistance, and predicted human pathogenicity(Frontiers Media SA, 2026-06-16) García-Candela, Jose Luis Enrique; Mondragón-Martínez, Aarón Maguín; Moreno-Morales, Gerald; Cabrera-Soregui, Milagros; Puicón-Niño-De-Guzmán, Víctor Humberto; Ramos-Gorbeña, Juan Carlos; Santa-Cruz, Alcides Guerra; Cruz-Neyra, Lidia; Solis-Sarmiento, JulioIntroduction – Aquaculture systems function as dynamic ecological interfaces facilitating the circulation of opportunistic pathogens and antimicrobial resistance (AMR) determinants across environmental, animal, and human compartments. Aeromonas spp. are ubiquitous freshwater bacteria and emerging human opportunistic pathogens, yet genomic data from tropical South American aquaculture remain scarce. Methods – Nine Aeromonas isolates from Amazonian aquaculture facilities in Peru were subjected to whole-genome sequencing. Species identification was performed using Average Nucleotide Identity and phylogenomic reconstruction within a dataset of 112 genomes. Ribosomal MLST, comparative gene content analysis, virulence and resistome profiling, human pathogenicity prediction, and quinolone resistance-determining region (QRDR) screening were conducted. Phenotypic antimicrobial susceptibility testing was performed against five antibiotics. Results – Phylogenomic analysis revealed substantial genetic diversity among the analyzed isolates, encompassing Aeromonas hydrophila, Aeromonas caviae, and Aeromonas veronii, with no clustering by host species or production site. Ribosomal MLST assigned 8 distinct rSTs across the 9 isolates. Comparative genomic analysis identified 19, 486 gene clusters, of which a subset was shared across all genomes, while the majority were variably distributed, indicating extensive genomic diversity across Aeromonas spp. All isolates shared conserved colonizationand secretion-associated determinants, whereas major cytotoxic toxin genes were absent. PathogenFinder v2 predicted high probabilities of human pathogenicity (0.93–0.96) across all genomes. Resistome analysis identified genes associated with tetracycline, quinolone, sulfonamide, and β-lactam resistance, including intrinsic blaOXA and cphA, while QRDR screening identified mutations potentially associated with quinolone resistance. Genomic findings were broadly consistent with phenotypic susceptibility profiles. Conclusion – Amazonian aquaculture systems harbor genetically diverse Aeromonas lineages with conserved opportunistic virulence traits and clinically relevant AMR determinants. These findings highlight the role of aquaculture environments as reservoirs and potential transmission interfaces of antimicrobial resistance and opportunistic pathogens, underscoring the importance of genomic surveillance within a One Health context.Item Lactic acid bacteria from Amazonian fruits: Isolation and evaluation of probiotic potential(Wiley, 2026-06-11) Pillaca-Pullo, Omar Santiago; Ortiz‐Saravia, Ana M; Mendoza‐Quezada, Marjorie; Lopes, André M; Huaman‐Susanibar, Adela I; Villacrés-Vallejo, Jorge Ysaac; Bautista‐Cruz, NelsonBACKGROUND Lactic acid bacteria (LAB) are a well-recognized group of probiotic microorganisms with proven health benefits and wide-ranging applications in food, pharmaceutical, and cosmetic industries. Although LAB have been extensively studied in fermented foods, their occurrence in plant-based environments, particularly in tropical fruits, remains poorly characterized. The Amazon biome, with its exceptional biodiversity and unique climatic conditions, offers an untapped reservoir of microbial diversity that could harbor novel probiotic strains. This study investigated three Amazonian fruits, such as Genipa americana, Pouteria caimito (domesticated fruits), and Solanum mammosum (native fruit) for the isolation and characterization of potentially probiotic LAB. RESULTS From 72 total isolates, 06 strains obtained from P. caimito were non-hemolytic and selected for in vitro probiotic assessment. Molecular identification revealed that these isolates belonged to the genera Lactobacillus, Pediococcus, and Lactiplantibacillus. Among them, isolate POU-25 (Lactiplantibacillus plantarum) exhibited superior probiotic features, including tolerance to acid and bile salts, strong autoaggregation and coaggregation with pathogens, and high surface hydrophobicity, traits associated with gastrointestinal survival and host adhesion. CONCLUSION These findings expand the current understanding of LAB diversity in Amazonian fruits and position Lactiplantibacillus plantarum POU-25 as a promising candidate for future use in functional foods and beverages. Moreover, its potential for the sustainable biosynthesis of value-added compounds, such as lactic acid, underscores its industrial relevance in the pharmaceutical and cosmetic sectors. © 2026 Society of Chemical Industry (SCI).Item Sequential electrocoagulation–ozonation treatment: Effect of suspended solids removal on sulfide elimination in tannery wastewater(Journal of Ecological Engineering, 2026-07-01) Aguilar-Ascón, Edwar; Marrufo-Saldaña, Liliana del Rosario; Barra-Hinojosa, Julio AlexisThe treatment of tannery wastewater is a complex environmental challenge. These effluents have high loads of total suspended solids (TSS) and, especially, sulfides, pollutants that require advanced technologies due to their toxicity and difficulty in removal. This study presents and evaluates an integrated electrocoagulation (EC) and ozonation (O3) system as an alternative for the comprehensive treatment of this effluent. In the EC stage, it was optimized using the response surface methodology (RSM) with a 3k factorial design, using current intensity (I) and treatment time (t) as factors to maximize TSS removal. The EC results demonstrated high TSS removal efficiency, reaching 97.91% under optimal conditions (p < 0.05), which significantly facilitates subsequent treatment. The most critical finding of the study lies in the ineffectiveness of EC for dissolved contaminants: the removal of sulfides was extremely limited, with an efficiency of only 4.2%. In contrast, the subsequent ozonation stage achieved more than 99% elimination of sulfides using a dose of 12 g h-1 of ozone after 20 minutes of reaction. This result justifies the need for an integrated system, where EC handles the load of solids (TSS) and other contaminants and ozonation performs the essential chemical oxidation of sulfides. The operating cost of the combined EC–O3 treatment was determined to be US$ 0.707 m-3, demonstrating the economic viability of the technology. The results confirm that the EC–O3 system is a synergistic solution for the environmental management of tannery wastewater, enabling compliance with maximum permissible limits.Item Evaluation of effluent treatment from paiche skin dyeing with juglone using electrocoagulation and ozonation: Removal performance and toxicity on Lactuca sativa(Ecological Engineering & Environmental Technology, 2026-07-01) Perez-Muñoz, Delia; Marrufo-Saldaña, Liliana del Rosario; Barra-Hinojosa, Julio Alexis; Aguilar-Ascón, EdwarThe application of walnut-based dyes in leather dyeing represents a less polluting process compared to the use of synthetic dyes; however, it still requires the evaluation and treatment of the generated effluents. The present study evaluated the efficiency of COD removal through the application of electrocoagulation and ozonation processes for the treatment of effluents generated during the dyeing of paiche skins using a walnut leaf-based dye. Subsequently, bioassays using Lactuca sativa seeds were conducted to assess the toxicity of both treated and untreated effluents, as well as the natural walnut-based dye and reference synthetic dyes. Optimal conditions for the electrocoagulation process were identified at a treatment time of 30 min and a current intensity of 7 A, achieving a COD removal efficiency of 51.67%. The application of ozonation as a complementary process to electrocoagulation resulted in an additional maximum removal of 12.51%. The bioassays indicated a reduction in toxicity in effluents treated by electrocoagulation compared to the untreated effluent. Regarding the dyes, the natural walnut-based dye exhibited higher toxicity than the synthetic dyes; however, this toxicity is associated with the active compound juglone, which has known phytotoxic activity.Item Valorization of Hydrobiological Waste through Anaerobic Fermentation for Biofertilizer Production(Chemical Engineering Transactions, 2026-02-16) Llenque-Paiva, Danny Wilfredo; Crisanto, Carlos A.; Burga, Tatiana M.; Manayay, Karyn L.; Jimenez, Juan E.; Rivera, William A.This study concerns the production of liquid biofertilizers by anaerobic fermentation of hydrobiological residues of A. purpuratus (Peruvian scallop), Oreochromis sp. (tilapia), O. mykiss (rainbow trout), and various marine wastes at concentrations of 20 %, 40 %, and 60 % (w/v), employing the commercial microbial consortium Garlac as inoculum. The objective was to characterize their physicochemical and microbiological properties and to assess their agronomic efficacy on Zea mays L. growth. Fermentation was achieved within 10 days, yielding biofertilizers with elevated organic matter content (83.83–97.74 %), organic carbon (48.63–56.70 %), and NPK concentrations of 0.50–1.19 % of N, 0.10–2.76 % of P, and 0.04–0.66 % of K. Germination bioassays demonstrated low phytotoxicity at 10-2 and 10-3 dilutions (germination index > 80 %), whereas the 10-1 dilution exhibited severe phytotoxicity attributed to acidic pH (3.95–4.57) and elevated electrical conductivity (22.40–32.40 mS/cm). Greenhouse trials revealed that biofertilizer applications enhanced maize plant height by 11.54–54.96 % relative to chemical fertilizer treatment after 60 days, with the 60 % marine waste biofertilizer distinguished by superior nitrogen content (1.19 %) and the 60 % tilapia biofertilizer by higher phosphorus concentration (2.76 %). The findings substantiate that valorization of hydrobiological wastes through anaerobic fermentation generates efficacious organic biofertilizers, thereby supporting Circular Economy principles within aquaculture and fisheries sectors. Copyright © 2026, AIDIC Servizi S. r. l.Item Modified Tuber Starches as Sustainable Biopolymers for the Encapsulating Bioactive Compounds: A Comprehensive Review(MDPI AG, 2025-12-07) Samaniego-Rafaele, César; Salvador-Reyes, Rebeca; Quispe-Santivañez, Grimaldo; Barriga-Sánchez, Maritza ElizabethModified tuber starches have gained relevance as innovative and versatile materials for the encapsulation of bioactive compounds, distinguishing themselves from synthetic polymers due to their biocompatibility, biodegradability, and tunable functionality. This review analyzes the effects of physical, chemical, and biochemical modifications on the composition and morphological, rheological, thermal, and techno-functional properties of tuber starches, as well as their development prospects as coating materials in encapsulation techniques such as spray drying, freeze-drying, electrospinning, and emulsification. The evidence reviewed indicates that modified tuber starches exhibit reduced retrogradation, higher thermal resistance, improved solubility, and better digestibility, facilitating their application as protective agents. The main challenges for their industrial implementation are identified and analyzed, including the standardization of processes, scalability, and the ambiguous regulatory framework. In the future, research in this area should be directed toward the optimization of “clean-label” methodologies and the valorization of non-conventional tuber sources, thereby consolidating the development of safer, more effective, and more sustainable encapsulation systems for the food industry.Item Quantitative analysis of factors affecting IR-43 and Tinajones rice variety adoption in Peru’s Camaná Valley(Springer Science and Business Media LLC, 2025-06-18) Zegarra-Flores, Jorge Arturo; Montalvo-Otivo, Jorge Manuel; Atao-Surichaqui, Elisa Raquel; Calizaya-Llatasi, Elmer Elio; Calizaya-Llatasi, Fredy Grimaldo; Mindani-Cáceres, Carmen Gisela; Caira-Mamani, Cirilo Mario; Ore-Areche, Franklin; Paricanaza-Ticona, Danitza Corina; Leon-Gomez, Rodolfo; Tito-Quispe, Edson EfraínThis study analyzed the socio-economic, institutional, and environmental factors influencing the adoption of highyielding rice varieties, IR-43 and Tinajones, in the Camaná Valley, Peru. Using a mixed-methods approach over 24 months, data were collected from 300 farmers through surveys, semi-structured interviews, and environmental assessments using life cycle analysis (LCA). Regression analysis identified farm size, access to credit, and institutional support as the primary drivers of adoption, with larger farms exhibiting adoption rates 40% higher than smaller ones due to better financial resources. Education and market access also significantly influenced adoption, with educated farmers and those with strong market integration showing a 25% higher likelihood of adoption. However, adoption came with environmental trade-offs: IR-43 and Tinajones required 10–20% more water and produced 15% higher greenhouse gas emissions than traditional varieties. Structural equation modeling revealed that education and institutional support indirectly increased yields by 30% through improved access to credit and training. The findings underscore the need for policy interventions that balance socio-economic benefits with environmental sustainability, integrating measures such as optimized irrigation and organic fertilization to mitigate negative environmental impacts. These findings highlight the need for integrated policy interventions that support both the socio-economic and environmental sustainability of rice farming in semi-arid regions like the Camaná Valley.Item Comparative chemical composition and antioxidant capacity of essential oil and oleoresin from Eucalyptus globulus Labill. leaves(Editorial CSIC, 2025-06-30) Barriga-Sánchez, Maritza Elizabeth; Arpi-Anco, Eliud Dennis; Cueva-Martínez, Pedro Miguel; Medina-Cáceres, Erika Amalia; Varas-Condori, Miguel ÁngelThe Eucalyptus globulus is a tree which is cultivated in Peru for its wood, while its leaves are often discarded. This study compared the extraction yield, chemical composition, and antioxidant capacity of essential oil and oleoresin obtained from the leaves. The essential oil was extracted by hydrodistillation (1.62 % yield), and oleoresins were obtained using supercritical CO2, with and without ethanol as a co-solvent (yield up to 8.96 %). GC-MS analysis identified 1,8-cineole as the major compound in the essential oil and in the oleoresin extracted with supercritical CO2+ethanol. The essential oil showed a higher monoterpene content (80.33 %), while the oleoresins were richer in sesquiterpenes (up to 63.68 %). The total phenolic content was significantly higher in the oleoresin (5.05-11.30 mg GAE/g) than in the essential oil (0.25 mg GAE/g). Antioxidant capacity was also significantly higher in the oleoresins. These findings highlight the potential of E. globulus oleoresin as a natural antioxidant for food and pharmaceutical applications.Item Production of bacterial cellulose by spontaneous fermentation of grape pomace and its thermal, mechanical, and spectroscopic characterization(Department of Polymer Engineering, Scientific Society of Mechanical Engineering, 2026-01) Gavilan-Figari, Isabel MilagrosBacterial cellulose (BC) is an eco-friendly biopolymer with outstanding structural and functional properties, offering promising applications in sustainable packaging and bio-based materials. In this study, we demonstrate the feasibility of producing BC via spontaneous fermentation, using grape pomace supplemented with sucrose as the sole carbon source, nutrient substrate, and microbial inoculum, without the addition of commercial strains or nitrogen supplements. Fermentation was conducted under static conditions, yielding biofilms with stable structural characteristics and BC production of up to 14.1 g/L, thereby confirming the efficiency of this low-cost, residue-based process. The films obtained exhibited well-organized polymeric networks, with thermal stability in the range of Tg ≈ 159–266 °C and mechanical resistance comparable to or higher than conventional biopolymers. Characterization confirmed reproducible chemical profiles, thermal stability, and measurable variation in mechanical performance, with a tensile strength ranging from 0.0001 to 105 MPa and an elongation at break of 15±5%. The process highlights a resource-efficient and sustainable pathway, adaptable to rural contexts and aligned with circular economic principles. While minor variations among replicates reflected the intrinsic variability of biological systems, mean values and standard deviations demonstrated reproducible physicochemical and mechanical properties. These findings demonstrate that BC derived from agro-industrial residues can be produced under simple, low-input conditions, opening opportunities for scalable valorization in functional and sustainable materials.Item Complete mitochondrial genome assembly and analysis of a Neotropical lineage of Ligula intestinalis reveals evolutionary and phylogenetic insights(Springer Science and Business Media LLC, 2026-02-17) Mondragón-Martínez, Aarón Maguín; Martínez-Rojas, Rosa; Gárate, Inés; Sánchez-Venegas, Jaime R; Moreno-Morales, Gerald; Cruz-Neyra, Lidia; Cruces, Celso Luis; García-Candela, Jose Luis Enrique; Guzman-Escudero, Frank; Chero, Jhon D; Yunis-Aguinaga, Jefferson; Štefka, Jan; Nazarizadeh, MasoudLigula intestinalis (Cestoda: Diphyllobothriidea) is a cosmopolitan tapeworm parasite characterized by a complex life cycle that includes freshwater fish infection. Ligula disrupts host reproduction, and causes ecological imbalances. Despite its broad geographic distribution and ecological significance, molecular data for South American populations have been lacking, leaving a critical gap in understanding its genetic diversity and evolutionary history. To address this, we conducted the first molecular characterization of L. intestinalis plerocercoid larvae isolated from the native fish Orestias agassizii in Lake Titicaca, Peru. Using Illumina next-generation sequencing, we assembled a complete mitochondrial genome of 13,657 bp, containing 12 protein-coding genes, 22 tRNA genes, two rRNA genes, and two non-coding regions. The mitogenome exhibited an A + T-rich composition (66.3%) and contained over 580 repetitive elements, primarily concentrated within its control region. Comparative analyses with European and Asian mitogenomes revealed substantial regional differences in nucleotide diversity and amino acid composition, with closer similarity observed between South American and Asian lineages. Genes atp6, nad5, and nad6 showed the highest variability, whereas cox1 demonstrated significant intercontinental divergence yet remained conserved within South America, reflecting both phylogeographic patterns and strong functional constraints. Phylogenetic inference based on mitochondrial markers (cytb, cox1, and nd1) confirmed the Titicaca specimen as a distinct South American lineage, closely related to the Nearctic lineage. These findings enhance our understanding of L. intestinalis mitogenomic diversity, emphasize the importance of geographic isolation in parasite diversification, and provide an essential genomic resource for future evolutionary and ecological research in high-altitude ecosystems.Item Efecto del método de conservación, bodega insulada vs. método tradicional sobre las características nutricionales, sensoriales y microbiológicas de Psectrogaster rutiloides y Potamorhina altamazonica(Universidad Nacional Mayor de San Marcos, Facultad de Medicina Veterinaria, 2026-02-27) Rivadeneyra-Sánchez, Norma Lorena; Moreno-Ríos, Christiaan Errol; Ferré-Rodríguez, Walter Richar; Bustillos-Aponte, Gino Vladimir; Vara-Valverde, Carlos Augusto; Soria-Torres, Ingrid Iris Manuela; Morales-Vilca, Janet; Pérez-Flores, Wendy Mishell; Maslucan-Canayo, Óscar André; Panduro-Vásquez, ÁngelEl trabajo tuvo como objetivo evaluar el efecto de dos métodos de conservación de pescado, bodega insulada vs. método tradicional, sobre las características nutricionales, sensoriales y microbiológicas de Psectrogaster rutiloides y Potamorhina altamazonica. La bodega insulada fue fabricada con estructura de madera, revestida de fibra de vidrio matt y resina, de 251.8 × 159.3 × 86.9 × 8.0 cm, y con drenaje a un extremo basal de dos pulgadas. El método tradicional correspondió a uso de plástico simple para revestir el interior de una embarcación pesquera artesanal simulando un «cajón isotérmico». Ambas estructuras fueron diseñadas para adaptarse al formato interno de una embarcación de pesquería artesanal. Se capturaron 175 kg de pescado de las dos especies en la zona de pesca del Caserío Palestina, Ucayali, Perú. El pescado fue colocado al interior del método de conservación correspondiente con hielo picado 1:1, tapado por cinco días, e inmediatamente transportado a laboratorio. El contenido de humedad, proteínas totales, extracto etéreo y cenizas determinado en cada especie no fue afectado por el método de conservación. La carne de las dos especies no excedió los límites máximos permisibles en cuanto a presencia de aerobios mesófilos totales, Staphylococcus aureus y Salmonella spp. Para Escherichia coli se evidenció menor preservación bajo el método de conservación tradicional. Finalmente, se obtuvieron valores aceptables con el método de índice de calidad (entre 9 a 13) para las dos especies en ambos métodos de conservación. Los dos métodos garantizan el buen estado del pescado P. rutiloides y P. altamazonica dentro de cinco días de conservación, con mejor ventaja para la bodega insulada en cuanto a mayor estabilidad de las condiciones microbiológicas.Item Optimization of the extraction of Curcuma longa L. oleoresin with supercritical CO2. Evaluation of antioxidant and hypoglycemic activity.(Academia Brasileira de Ciências, 2025) Barriga-Sánchez, Maritza Elizabeth; Cueva-Martínez, Pedro Miguel; Sanchez-Gonzales, Gloria Cesia; Gonzalez-Aspajo, Germán; Villacrés-Vallejo, Jorge YsaacThe fresh rhizomes and flour of turmeric (Curcuma longa L.) have been used for centuries in traditional medicine to treat ailments. In recent years, attention has been paid to the beneficial properties of turmeric such as the prevention and control of diabetes. The objectives of this study were to optimize the extraction parameters of turmeric oleoresin (TO) with supercritical CO2 and ethanol (SC-CO2), and to evaluate the antioxidant activity and hypoglycemic activity in vitro and in vivo. The results showed that the optimal conditions for oleoresin extraction using SC-CO2 were 188 bar, 65°C and 180 min; the yield obtained under optimal conditions was 16.09 ± 0.57 oleoresin/100 g turmeric flour; antioxidant activity (ABTS) was 2224.96±26.33 μmol TE/g oleoresin; the mean inhibitory concentration of α-glucosidase (IC50) was 11.59 ± 2.05 μg/mL; and the greatest hypoglycemic effect in vivo in mice was obtained at the concentration of 200 mg of TO /kg body weight. This work shows the optimized conditions to extract the greatest amount of TO with the highest content of curcuminoids and antioxidant activity, and the in vitro and in vivo hypoglycemic effect of TO, for its possible use in functional foods.Item In vitro and in vivo evaluation of hypoglycemic potential and acute toxicity of microencapsulated turmeric instant powder(Phytomedicine Plus, 2024-11-01) Barriga-Sánchez, Maritza Elizabeth; Gonzalez-Aspajo, Germán; Sanchez-Gonzales, Gloria Cesia; Barreto-Salcedo, Candy; Aranda-Ventura, Jose AlbertoBackground: Curcuma longa L. (turmeric), traditionally used to treat various ailments including diabetes, has demonstrated beneficial health effects. However, its potential in food formulations requires further investigation. Purpose: This study examined the hypoglycemic effects of an instant powder containing microencapsulated turmeric oleoresin both in vitro and in vivo, alongside an acute toxicity assessment in Holtzman rats. Methods: This study encompassed both in vitro and in vivo evaluations. In vitro, the α-glucosidase (a digestive enzyme) inhibition assay was employed to determine the powder's effectiveness. In vivo assessments included: (1) evaluation of the hypoglycemic effect in mice; (2) conducted safety testing following international guidelines, administering a 2000 mg/kg dose to rats with subsequent monitoring of biochemical parameters; and (3) histological examination of liver, kidney, and spleen tissues for potential harmful effects. Results: The instant powder with turmeric oleoresin microencapsulation demonstrated significant α-glucosidase inhibition in vitro and hypoglycemic effects in vivo. The acute toxicity test at 2000 mg/kg showed no mortality but revealed significant alterations in erythrocyte parameters and hemoglobin percentage. Histological examinations of liver, kidney, and spleen tissues did not differ from those of the control group, though pancreatic tissue was not evaluated in this study. Conclusion According to this study, the microencapsulated turmeric oleoresin instant powder exhibited antidiabetic effects without signs of overt toxicity at doses up to 2000 mg/kg in rats.Item OPTIMIZACIÓN DEL RENDIMIENTO DE LA EXTRACCIÓN DE ACEITE DE SEMILLAS DE Vitis vinifera CON CO2 SUPERCRÍTICO(Sociedad Química del Perú, 2018) Barriga-Sánchez, Maritza Elizabeth; Churata-Huanca, Anna Clara; Tinoco-Gomez, ÓscarSe optimizó el rendimiento de la extracción de aceite de la semilla de uva, variedad Quebranta, con el método superficie respuesta (MSR), se consideraron tres factores: presión (Pbar), temperatura (T) y flujo de CO2 (F), las variables respuesta fueron el rendimiento de aceite, el valor peróxido (POV) y anisidina. Se caracterizó la semilla y estableció el tamaño de partícula de la semilla para la extracción de aceite. Se realizaron las extracciones según el diseño MSR y se calcularon los rendimientos de aceite, POV y anisidina. Se determinó la composición de ácidos grasos por cromatografía de gases y la actividad antioxidante por reducción del radical 1,1-difenil-2-picrilhidrazil (DPPH) del aceite optimizado obtenido con CO2 y del extraído con hexano (testigo). La Pbar, T y F ejercieron efecto significativo sobre el rendimiento, pero no ejercieron efecto sobre el POV y anisidina. Los resultados son prometedores para añadir valor agregado a la semilla, residuo de la elaboración de pisco ya que el aceite contenía 66,45 % de ácido linoléico; 20,05 % de ácido oleico y una capacidad antioxidante de 7,80 mM equivalente a Trolox.